Ac-IETD-pNA, Caspase-8 Chromogenic Substrate (TBP0138)

Description

Ac-IETD-pNA is a colorimetric substrate specifically designed for caspase-8, a cysteine protease involved in apoptosis signaling pathways. This substrate contains the peptide sequence Ile-Glu-Thr-Asp (IETD), which is selectively recognized and cleaved by caspase-8. This makes Ac-IETD-pNA a useful tool for assessing caspase-8 activity in biochemical assays and apoptosis research.

Product Details

Formal Name: N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-(4-nitrophenyl)-L-α-asparagine

Alternate Names: Ac-Ile-Glu-Thr-Asp-pNA; Caspase-8 Chromogenic Substrate I

Molecular Formula: C₂₇H₃₈N₆O₁₂

Formula Weight: 638.6

CAS Number: 219138-21-3

Purity: ≥98%

Formulation: powder

Storage: -20°C

Stability: >4 years

Solubility: Formic Acid: 1 mg/ml

Research use only.

Additional information

Datasheet:

TBP0138-AC-IETD-pNA_datasheet

MSDS:

TBP0138_Ac-IETD-pNA_MSDS

Research use only.