TO1-3PEG-Biotin Fluorophore (TBS6106)

Description

RNA Mango technology is based on the specific binding of the RNA Mango Aptamer and a Thizole Orange (TO) bi-functional dye. Features of this technology are the tight binding between the dye and aptamer (KD ≈ 3nM), and the strong ~1000X enhancement of the dye’s fluorescence when bound to the Mango apatmer (Fluorescent enhancement FE=1,100). The TO dye has a number of other desirable properties including:

• small size
• lack of toxicity
• plasma and nuclear membrane permeability
• short intracellular half-life
• the accessibility of a broad wavelength range simply via substitutions and alterations to the TO structure

TO1-biotin is the standard variety of TO dye for in vitro and in vivo RNA Mango and RNA Peach experiments.

Component

Store at -20°C. Protect from light.

Research use only.

Additional information

Datasheet:

TBS6106-TO1-3PEG-Biotin Fluorophore_datasheet

MSDS:

TBS6106_TO1-3PEG-Biotin Fluorophore_MSDS

Research use only.