TO1-3PEG-Desthiobiotin Fluorophore (TBS6107)

Description

TO1-3PEG-Desthiobiotin is a small bifunctional fluorophore that allows for the recovery of native RNA complexes while simultaneously rendering them highly fluorescent. The bound fluorescent complex of Mango I and TO1-3PEG-Desthiobiotin is bright and when bound next generation aptamers (Mango III and IV) have a brightness that exceeds that of enhanced GFP. When bounded to steptavidin, can be eluted by the addition of free biotin allowing for the recovery of complexes that can be further purified (i.e. size chromatography).

The TO dye has a number of other desirable properties including:

• small size
• lack of toxicity
• plasma and nuclear membrane permeability
• short intracellular half-life
• the accessibility of a broad wavelength range simply via substitutions and alterations to the TO structure

TO1-biotin is the standard variety of TO dye for in vitro and in vivo RNA Mango and RNA Peach experiments.

Component

Store at -20°C. Protect from light.

Research use only.

Additional information

Datasheet:

TBS6107-TO1-3PEG-Desthiobiotin Fluorophore_datasheet

MSDS:

TBS6107_TO1-3PEG-Desthiobiotin Fluorophore_MSDS

Research use only.