InVivoMAb Anti-Human IL1B/IL1F2 Antibody (TBS10346)

$489.00$2,399.00

Target: Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta, IL-1β.

SKU: TBS10346 Categories: ,
SKUStock SIZE (mg) PriceQuantity
TBS10346-0.5MG Yes 0.5 MG $489.00
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TBS10346-1MG Yes 1 MG $719.00
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TBS10346-5MG Yes 5 MG $2,399.00
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Description

InVivoMAb Anti-Human IL1B/IL1F2 antibody is a monoclonal antibody designed to specifically neutralize human interleukin-1 beta (IL-1β), also known as IL-1F2, a key pro-inflammatory cytokine involved in innate immune responses. By blocking IL-1β signaling, this antibody effectively attenuates downstream inflammatory pathways. It is widely used in preclinical and translational research to investigate the role of IL-1β in autoinflammatory and inflammatory diseases, including cryopyrin-associated periodic syndromes (CAPS), tumor necrosis factor receptor–associated periodic syndrome (TRAPS), familial Mediterranean fever (FMF), Still’s disease, and gout flares.

Synonyms: Anti-Human IL-1β monoclonal antibody, Anti-IL1B antibody, Anti-IL-1 beta antibody, IL-1β neutralizing antibody, IL-1F2 antibody, Human IL-1β blocking antibody, Anti-IL-1β mAb, functional grade IL-1β antibody, neutralizing anti-IL-1β antibody.

Product Details

Applications: ELISA, FCM, Neutralization.
Species reactivity: Human
Host: Human
Isotype: IgG1, kappa
Target: Interleukin-1 beta, IL1B, Catabolin, IL1F2, IL-1 beta, IL-1β.
Uniprot: P01584
Concentration: 3 mg/ml
Purity: >95%
Formulation: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Clonality: Monoclonal
Storage: Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles.

 Data Image

 

Fig. 1. SDS-PAGE for InVivoMAb Anti-Human IL1B/IL1F2 antibody

MW: Molecular Weight (kDa) Marker.

R: Reducing conditions.

NR: Non-Reducing conditions.

 

 

Fig. 2. Flow-cytometry using anti-human IL1B antibody. HeLa cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human IL1B antibody monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody and cells analysed on a NovoCyte Flow Cytometer.

Research use only.

Additional information

SIZE (mg)

1 MG, 5 MG, 0.5 MG

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