Recombinant Mouse CD38 Protein (His Tag), Enzymatic Activity (TBP0005)
$398.00 – $2,400.00
SKU | Stock | SIZE | Price | Quantity | ||
---|---|---|---|---|---|---|
TBP0005-50UG | Yes | 50 µg | $398.00 | |||
TBP0005-500UG | Yes | 500 µg | $2,400.00 |
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Description
Product Description
Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells. This enzyme is validated for CD38 Enzymatic activity application.
Product Details
Source: Mouse
Expression system: HEK293 Cells.
Protein Construction: Met1-Thr304 with a C terminal 6 His tag.
UniProt No: P56528
Alternative Names: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CD38, ADPRC 1, ADPRC1.
Product Specification
N Terminal Sequence Analysis: Leu 45.
Predicted Molecular Weight: 31.3 kDa (271aa)
SDSPAGE: 38-42 kDa in SDS-PAGE under reducing conditions.
Concentration: 1mg/ml.
Formulation: Liquid in 50mM MES buffer (pH 6.5) containing 100mM NaCl, 10% glycerol.
Concentration: 1mg/mL.
Purity: > 95% by SDS-PAGE.
Tag: His-Tag.
Biological Activity: Measured by its ability to convert the substrate nicotinamide guanine dinucleotide (NGD+) to cyclic GDP ribose. The specific activity is > 50,000 pmoles/min/μg.
Storage Condition: Store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Protein Sequence: Met1-Thr304.
Applications
Enzymatic Activity, and protein assay by SDS-PAGE
Additional information
SIZE | 50 µg, 500 µg |
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