Ac-LETD-AFC, Caspase-8 Substrate (TBP0115)
$248.00 – $436.00
Alternative names: N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-8 Substrate (Fluorogenic)
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBP0115-5MG | Yes | 5 MG | $248.00 | |||
| TBP0115-10MG | Yes | 10 MG | $436.00 |
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Description
Ac-LETD-AFC is a fluorogenic substrate specifically designed for detecting caspase-8 activity, an essential protease involved in the extrinsic apoptosis pathway. Upon cleavage by active caspase-8, the AFC moiety is released, emitting a measurable fluorescent signal. The free AFC exhibits an excitation maximum at 400 nm and an emission maximum at 505 nm, facilitating sensitive and specific detection of caspase-8 activity in various biological samples.
Product Details
Formal Name: N-acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine
Molecular Formula: C31H38F3N5O12
Formula Weight:729.7
CAS Number:210345-02-1
Purity: > 95%
Formulation: powder
Storage: -20°C
Stabilizer: >4 Years.
Solubility: DMSO: 10 mg/ml
Application: Caspase-8 activity determination
Research use only.
Additional information
| SIZE (mg) | 10 MG, 5 MG |
|---|
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