VH032 amine HCl, VHL ligand for PROTACS (TBI3458)

Description

Product Details

Formal Name: (4R)-3-Methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-L-prolinamide dihydrochloride

Molecular Formula: C₂₂H₃₀N₄O₃S.2HCl

Formula Weight: 503.49

CAS Number: 2137142-47-1

Purity: ≥98%

Formulation: powder

Solubility: DMSO (100 mg/ml)

Storage: -20°C

Stability: ≥ 1 year

Applications

VHL ligand for PROTACS

Functions

VH032 amine HCl is a derivative of the von Hippel-Lindau (VHL) ligand VH032, commonly used as a precursor to PROTACs. It is typically conjugated to a linker or target protein ligand.

Application Procedures

First dissolved in DMSO (100 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Research use only.

Additional information

Datasheet:

TBI3458_VH032 amine HCl_datasheet

MSDS:

TBI3458_VH032 amine HCl_MSDS_2024

Research use only.