TAME, Ubiquitin ligase inhibitor (TBI1364)

Description

Product Details

Formal Name: N-p-Tosyl-L-arginine methyl ester hydrochloride

Molecular Formula: C₁₄H₂₂N₄O₄S ∙ HCl

Formula Weight: 378.87

CAS Number: 1784-03-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml) or in Water (up to 30 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

 

Applications

Ubiquitin ligase inhibitor

 

Functions

TAME binds to the ubiquitin ligase anaphase-promoting complex (APC) preventing its activation by Cdc20 and Cdh1 and resulting in mitotic arrest.

 

Application Procedures

First dissolved in DMSO (up to 30 mg/ml) or in Water (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Additional information

SIZE (mg)	500 MG, 100 MG

TBI1364_TAME