Scriptaid, HDAC inhibitor (TBI2712)
$135.00 – $486.00
HDAC inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2712-5M | Yes | 5 MG | $135.00 | |||
TBI2712-25MG | Yes | 25 MG | $486.00 |
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Description
Product Details
Formal Name: 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide
Alternate Names: Scriptide; GCK1026
Molecular Formula: C18H18N2O4
Formula Weight: 326.35
CAS Number: 287383-59-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 4 mg/ml)
Storage: RT
Stability: ≥ 2 years.
Applications
HDAC inhibitor
Functions
Inhibits histone deacetylases (HDAC) 1 and 3 (IC50~0.6 µM) and HDAC8 (IC50~1 µM) and is less toxic compared to trichostatin A. Induces cell cycle arrest and epigenetic changes in colon cancer cells. Together with DRB-inhibition of RNA synthesis, scriptaid enhances gene reprogramming in somatic cell nuclear transfer (SCNT) embryos. Increases exercise endurance in mice.
Application Procedures
First dissolved in DMSO (up to 4 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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