SB-216763, GSK-3 inhibitor (TBI2338)
$99.00 – $342.00
GSK-3 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2338-5MG | Yes | 5 MG | $99.00 | |||
TBI2338-25MG | Yes | 25 MG | $342.00 |
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Description
Product Details
Formal Name: 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Molecular Formula: C19H12Cl2N2O2
Formula Weight: 371.23
CAS Number: 280744-09-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
GSK-3 inhibitor
Functions
Potent and selective inhibitor of glycogen synthase kinase-1 (GSK-3) IC50=34.3 nM. Acts at the ATP-binding domain. Displays protective effects in lung fibrosis mouse model. Displays neuroprotective effects on cultured neurons. Maintains mouse embryonic stem cells in a pluripotent state. Cell permeable.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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