Pyrintegrin, ß1-integrin agonist (TBI5468)

Description

Product Details

Formal Name: N-(Cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]-benzenesulfonamide

Molecular Formula: C₂₃H₂₅N₅O₃S

Formula Weight: 451.5

CAS Number: 1228445-38-2

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (45 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

ß1-integrin agonist

Functions

β1-integrin agonist that promotes survival of human embryonic stem cells following enzymatic dissociation by enhancing cell-ECM-mediated integrin activity. It induces soft tissue formation from transplanted or endogenous cells via stimulation of adipogenesis and may have potential in soft tissue therapeutic reconstruction and augmentation, It protects podocytes from LPS-induced injury in vivo. A very useful tool for exploring the involvement of β1-integrin signaling in cellular physiology.

Application Procedures

First dissolved in DMSO (45 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Research use only.

Additional information

Datasheet:

TBI5468_Pyrintegrin_datasheet

MSDS:

TBI5468_Pyrintegrin_MSDS

Research use only.