Kynurenine (L), Endogenous AhR agonist (TBI2666)
$68.00 – $158.00
Endogenous AhR agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2666-20MG | Yes | 20 MG | $68.00 | |||
TBI2666-100MG | Yes | 100 MG | $158.00 |
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Description
Product Details
Formal Name: L-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
Alternate Names: β-Anthraniloyl-L-alanine
Molecular Formula: C10H12N2O3
Formula Weight: 208.22
CAS Number: 2922-83-0
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Endogenous AhR agonist
Functions
Tryptophan catabolite. Endogenous tumor-promoting ligand of the human aryl hydrocarbon receptor (AhR). Constitutively generated by human tumor cells via the action of the tryptophan degrading enzyme, tryptophan-2,3-dioxygenase (TDO). Kynurenine suppresses antitumor immune responses and promotes tumor cell survival and motility.
Application Procedures
First dissolved in DMSO (up to 2 mg/ml) or in Water (up to 2 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 20 MG, 100 MG |
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