Flumazenil, Benzodiazepine antagonist (TBI1081)

Description

Product Details

Formal Name: 8-Fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, ethyl ester

Alternate Names: Ro 1722; Ro 15-1788

Molecular Formula: C₁₅H₁₄FN₃O₃

Formula Weight: 303.30

CAS Number: 78755-81-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 8 mg/ml).

Storage: -20°C

Stability: ≥ 2 years.

Applications

Benzodiazepine antagonist

Functions

A benzodiazepine antagonist, panspecific for α1, α2, α3 or α5-containing GABA_A receptors.  Reduces withdrawal sequelae in benzodiazepine dependence. Reverses the toxic effects, including coma and respiratory depression of zolpidem intoxication and gabapentin-induced coma.

Application Procedures

First dissolved in DMSO (up to 8 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Research use only.

Additional information

Datasheet:

TBI1081_Flumazenil_DataSheet

MSDS:

TBI1081_Flumazenil_MSDS

Research use only.