Chymostatin, Chymotryptase serine protease inhibitor (TBI2722)
$162.00 – $666.00
Chymotryptase serine protease inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2722-5MG | Yes | 5 MG | $162.00 | |||
TBI2722-25MG | Yes | 25 MG | $666.00 |
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Description
Product Details
Formal Name: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu, B=Val, C=Ile]-phenylalaninal
Molecular Formula: C31H41N7O6
Formula Weight: 605.00 (average)
CAS Number: 9076-44-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Chymotryptase serine protease inhibitor
Functions
A potent, competitive, slow-binding inhibitor of α-, β-, γ-, δ-chymotrypsin, papain and cathepsins B/G (chymotryptase-like serine proteases) Ki=9.36 and 13.1 nM for chymotrypsin and chymase. Cathepsin G Ki=0.15 μM. Consists of a mixture of type A (L-Leu), B (L-Val) and C (L-Ile) forms. Decreases plasma and tissue levels of angiotensin II without lowering mean blood pressure in a hypertensive rat model. Commonly used in lysis buffers to prevent degradation of proteins. Typical working concentration is 6-60 µg/ml.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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