Mocetinostat, Class I HDAC inhibitor (TBI3306)
$126.00 – $504.00
Class I HDAC inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3306-5MG | Yes | 5 MG | $126.00 | |||
TBI3306-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Formal Name: N-(2-Aminophenyl)-4-[(4-pyridin-3-ylpyrimidin-2-ylamino)methyl]benzamide
Alternate Names: MGCD0103
Molecular Formula: C23H20N6O
Formula Weight: 396.44
CAS Number: 726169-73-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml)
Storage: RT
Stability: ≥ 1 year.
Applications
Class I HDAC inhibitor
Functions
Class I, isoform-selective HDAC inhibitor, IC50s=0.15, 0.29, 1.66 and 0.59 μM for HDAC1, 2, 3 and 11 respectively. Induces hyperacetylation of histones, induces expression of the tumor suppressor p21WAF1 and inhibits proliferation of human cancer cells. Displays antifibrotic effects in ischemic heart failure. Attenuates the development of hypersensitivity in models of neuropathic pain. Active in vivo.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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