InVivoMAb Anti-Human CCL2 / MCP-1 antibody (TBS10329)

$489.00$2,399.00

Target: HC11, MCP-1, MCP1, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Small-inducible cytokine A2, SCYA2, MCAF, Monocyte secretory protein JE, C-C motif chemokine 2, Monocyte chemoattractant protein 1, CCL2.

SKU: TBS10329 Categories: ,
SKUStock SIZE (mg) PriceQuantity
TBS10329-0.5MG Yes 0.5 MG $489.00
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TBS10329-1MG Yes 1 MG $719.00
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TBS10329-5MG Yes 5 MG $2,399.00
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Description

InVivoMAb Anti-Human C-C Motif Chemokine Ligand 2 (CCL2) antibody is a human IgG1 monoclonal antibody that specifically targets CCL2. It reduces tumor-associated macrophage infiltration, slows tumor progression, and enhances the efficacy of chemotherapy.

Synonyms: Anti-Human CCL2 antibody, Anti-Human Monocyte Chemoattractant Protein‑1 antibody, Anti-Human MCP-1 antibody.

Product Details

Applications: ELISA, FCM, Neutralization
Species reactivity: Human
Host: Human
Isotype: IgG1, kappa
Target:

 

HC11, MCP-1, MCP1, Monocyte chemotactic protein 1, Monocyte chemotactic and activating factor, Small-inducible cytokine A2, SCYA2, MCAF, Monocyte secretory protein JE, C-C motif chemokine 2, Monocyte chemoattractant protein 1, CCL2.
Uniprot: P13500
Concentration: 3 mg/ml
Purity: >95%
Formulation: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Clonality: Monoclonal
Storage: Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles.

Data Image

Fig. 1. SDS-PAGE analysis of Anti-Human CCL2.                      

MW: Molecular Weight (kDa) Marker

R: Reducing conditions

NR: Non-Reducing conditions

Fig. 2. Western blot analysis was performed using anti-CCL2 monoclonal antibody at 1μg/ml on various samples.

Lane 1: recombinant human CCL2/MCP-1 50ng
Lane 2: recombinant human CCL2/MCP-1 30ng
Lane 3: recombinant human CCL2/MCP-1 20ng
Lane 4: recombinant human CCL2/MCP-1 10ng

Fig. 3. Flow-cytometry using anti-human CCL2 antibody. Human peripheral blood lymphocytes were stained with an irrelevant antibody (Blue Histogram) or an anti-human CCL2 antibody monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody and cells analyzed on a NovoCyte Flow Cytometer.

 

Fig. 4. Flow-cytometry using anti-human CCL2 antibody. A549 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CCL2 antibody monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody and cells analyzed on a NovoCyte Flow Cytometer.

 

Fig. 5. SEC-HPLC detection for InVivoMAb Anti-Human CCL2.

 

Research use only.

Additional information

SIZE (mg)

1 MG, 5 MG, 0.5 MG

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