InVivoMAb Anti-Human ARG1/Arginase-1 Antibody (TBS10330)

$489.00$2,399.00

Target: Liver-type arginase, ARG1, Type I arginase, Arginase-1.

SKU: TBS10330 Categories: ,
SKUStock SIZE (mg) PriceQuantity
TBS10330-0.5MG Yes 0.5 MG $489.00
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TBS10330-1MG Yes 1 MG $719.00
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TBS10330-5MG Yes 5 MG $2,399.00
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Description

The InVivoMAb Anti-Human ARG1 antibody is a monoclonal antibody directed against human Arginase 1 (hARG1), a metalloenzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea and plays a critical role in the regulation of T cell–mediated immune responses.

Synonyms: Anti-Arginase 1 Antibody, Anti-ARG1 Monoclonal Antibody, Human Arginase 1–Blocking Antibody, ARG1 Neutralizing Antibody, ARG1 Functional Inhibitory Antibody.

Product Details

Applications: ELISA, Flow Cytometry (FCM), Neutralization
Species reactivity: Human
Host: Mouse
Isotype: IgG2a, kappa
Target: Liver-type arginase, ARG1, Type I arginase, Arginase-1.
Uniprot: P05089
Concentration: 3 mg/ml
Purity: >95%
Formulation: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Clonality: Monoclonal
Storage: Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles.

Data Image

 

Fig. 1. SDS-PAGE analysis of Human ARG1 antibody

MW: Molecular Weight (kDa) Marker

R: Reducing conditions

NR: Non-Reducing conditions

 

Fig. 2. Detects Human ARG1 antibody in indirect ELISAs.

 

Fig. 3. Flow-cytometry using anti-human Arginase 1 antibody. Human peripheral blood lymphocytes were stained with an irrelevant antibody (Blue Histogram) or an anti-human Arginase 1 monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT.

Fig. 4. Flow-cytometry using anti-human Arginase 1 antibody. M2 macrophages derived from THP-1 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human Arginase 1 monoclonal antibody (Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT.

 

Fig. 5. Flow-cytometry using PE anti-human Arginase 1 antibody. HepG-2 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an PE anti-human Arginase 1 monoclonal antibody (Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analyzed on a NovoCyte Flow Cytometer.

 

 

 

Research use only.

Additional information

SIZE (mg)

1 MG, 5 MG, 0.5 MG

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