InVivo Anti-Mouse CD161/KLRB1/NK1.1 Antibody (TBS10338)
$249.00 – $1,299.00
Target: CLEC5B, KLRB1, CD161, HNKR-P1a, C-type lectin domain family 5 member B, NKRP1A, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1, NKR-P1A.
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBS10338-0.5MG | Yes | 0.5 MG | $249.00 | |||
| TBS10338-1MG | Yes | 1 MG | $359.00 | |||
| TBS10338-5MG | Yes | 5 MG | $1,299.00 |
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Description
InVivo Plus Anti-Mouse CD161 antibody recognizes mouse NK1.1 (CD161b/CD161c, KLRB1, NKR-P1A), a type II membrane glycoprotein with a C-type lectin domain encoded by Klrb1c. NK1.1 plays a key role in NK-cell activation, differentiation, IFN-γ production, and cytotoxic granule release, and is also expressed on a small subset of NK-T cells. NK1.1 is predominantly present as a disulfide-linked homodimer on NK cells. Expression of NK1.1 is strain-restricted, found in C57BL/6, FVB/N, and NZB mice, but absent in strains such as AKR, BALB/c, CBA/J, C3H, DBA, NOD, SJL, and 129. This antibody is suitable for in vivo applications, including depletion or functional modulation of NK cells and NK-T cells in mouse models.
Synonyms: NK1.1 antibody, CD161 antibody, Killer cell lectin-like receptor subfamily B member 1 (KLRB1) antibody, NKR-P1A antibody.
Product Details
| Applications: | In-vivo NK cell depletion, FCM. |
| Species reactivity: | Mouse |
| Host: | Mouse |
| Isotype: | IgG2a, kappa |
| Target: | CLEC5B, KLRB1, CD161, HNKR-P1a, C-type lectin domain family 5 member B, NKRP1A, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1, NKR-P1A. |
| Uniprot: | P27811 |
| Concentration: | 3 mg/ml |
| Purity: | >95% |
| Formulation: | Liquid |
| Storage buffer: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Clonality: | Monoclonal |
| Storage: | Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles. |
Data Image
Fig. 1. SDS-PAGE for InVivo Plus Anti-Mouse CD161/KLRB1/NK1.1 Antibody
MW: Molecular Weight (kDa) Marker
R: Reducing conditions
NR: Non-Reducing conditions
Research use only.
Additional information
| SIZE (mg) | 1 MG, 5 MG, 0.5 MG |
|---|
Datasheet:
TBS10338 InVivo Anti-Mouse CD161 Antibody_Datasheet
MSDS:
TBS10338_InVivo Anti-Mouse CD161 Antibody_MSDS
Research use only.
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