SU-4312, VEGFR / PDGFR kinase inhibitor (TBI1027)
$126.00 – $504.00
VEGFR / PDGFR kinase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1027-5MG | Yes | 5 MG | $126.00 | |||
TBI1027-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Formal Name: 3-(4-Dimethylaminobenzylidene)-1,3-dihydroindol-2-one
Molecular Formula: C17H16N2O
Formula Weight: 264.33
CAS Number: 5812-07-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
VEGFR / PDGFR kinase inhibitor
Functions
Potent selective inhibitor of VEGFR kinase (also known as Flk-1 and KDR). Inhibition of the activated kinase (IC50 = 0.4 µM) is 100-fold less than inhibition of the unactivated kinase (IC50 = 0.04 µM). Also inhibits PDGFR kinase (IC50 = 19.4 µM).
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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