WS6, Stimulates pancreatic beta-cell proliferation (TBI5666)
$135.00 – $504.00
Stimulates pancreatic beta-cell proliferation
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI5666-5MG | Yes | 5 MG | $135.00 | |||
TBI5666-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Formal Name: 4-[[6-[Cyclopropylcarbonyl)amino]-4-pyrimidinyl]oxy]-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzeneacetamide
Molecular Formula: C29H31F3N6O3
Formula Weight: 568.60
CAS Number: 1421227-53-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (30 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Stimulates pancreatic beta-cell proliferation
Functions
Stimulates human β-cell proliferation both in a dispersed islet proliferation assay and in intact human cultures. It has been shown to induce both α- and β-cell proliferation. May lead to the development of new therapeutics for diabetes. Induces adult hippocampal neurogenesis correlating with its antidepressant effect in a rat model of chronic unpredictable mild stress-induced depression. Has been used together with TTNPB and azakenpaullone, as a defined chemical cocktail to induce mouse totipotent stem cells. Cell permeable.
Application Procedures
First dissolved in DMSO (30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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