SR-9243, LXR agonist (TBI4579)
$81.00 – $315.00
LXR agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4579-5MG | Yes | 5 MG | $81.00 | |||
TBI4579-25MG | Yes | 25 MG | $315.00 |
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Description
Product Details
Formal Name: N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3’-(methylsulfonyl)[1,1’-biphenyl]-4-yl]methyl]-benzenesulfonamide
Molecular Formula: C31H32BrNO4S2
Formula Weight: 626.62
CAS Number: 1613028-81-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (greater than 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
LXR agonist
Functions
SR9243 is an LXR inverse agonist that significantly inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression. Induces apoptosis in a variety of cancer cell types including SW620 (IC50 = 40 nM), HT-29 (IC50 = 104 nM), DU-145 (IC50 = 15 nM), PC-3 (IC50 = 61 nM), NCI-H23 (IC50 = 72 nM), HOP-62 (IC50 = 26 nM) and MIAPACA-2 (IC50 = 18 nM). SR9243 is able to promote apoptotic cancer cell death without adversely affecting non-malignant cells.
Application Procedures
First dissolved in DMSO (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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