SU-1498, VEGFR kinase inhibitor (TBI2074)

Description

Product Details

Formal Name: (E)-N-(3’-Phenylpropyl)-α-cyano-3’,5’-diisopropyl-4’-hydroxycinnamamide

Molecular Formula: C₂₅H₃₀N₂O₂

Formula Weight: 390.52

CAS Number: 168835-82-3

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO.

Storage: -20°C

Stability: ≥ 1 year.

 

Applications

VEGFR kinase inhibitor

 

Functions

Potent, reversible, selective inhibitor of VEGFR-2, also known as Flk-1 (IC50 = 700 nM).   Inhibition of VEGFR-2 blocks angiogenesis in both in vitro and in vivo models.  Cell permeable.

 

Application Procedures

First dissolved in DMSO, then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.

Additional information

SIZE (mg)	25 MG, 5 MG

TBI2074_SU-1498