Milbemectin, RDL GABA agonist; Glutamate-gated Cl channel activator (TBI5257)
$198.00 – $792.00
RDL GABA agonist; Glutamate-gated Cl channel activator
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBI5257-5MG | Yes | 5 MG | $198.00 | |||
| TBI5257-25MG | Yes | 25 MG | $792.00 |
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Description
Product Details
Formal Name: Milbemectin is a mixture of Milbemycin A3 (~30%) and Milbemycin A4 (~70%)
Milbemycin A3: (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-methyl-milbemycin B
Milbemycin A4: (6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-milbemycin B
Molecular Formula: C32H46O7 (A4)
Formula Weight: 542.7 (A4)
CAS Number: 1799297-76-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (20 mg/ml); or Ethanol (40 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
RDL GABA agonist; Glutamate-gated Cl channel activator
Functions
An allosteric agonist at the Drosophila RDL GABA receptor. Also acts as an agonist at glutamate-gated chloride channels in insects. Mutations (specifically a G326E substitution) in the glutamate-gated chloride channel 3 (GluCl3) in phytophagous mites abolishes agonist activity resulting in resistance. Commercially used as an acaricide.
Application Procedures
First dissolved in DMSO (20 mg/ml); or Ethanol (40 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Research use only.
Additional information
| SIZE (mg) | 25 MG, 5 MG |
|---|
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