Dodecyl-TPP, Mitochondria-targeted cancer stem cell inhibitor (TBI3781)

Description

Product Details

Formal Name: Dodecyltriphenylphosphonium bromide

Molecular Formula: C₃₀H₄₀BrP

Formula Weight: 511.50

CAS Number: 15510-55-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO up to 50 mg/ml, or Ethanol (25 mg/ml)

Storage: RT

Stability: ≥ 2 years.

Applications

Mitochondria-targeted cancer stem cell inhibitor

Functions

A mitochondria-targeting agent which inhibits mitochondrial function inhibiting oxidative phosphorylation and shifting cell metabolism to glycolysis. Potently eradicates cancer stem cells (50 nm to 1 mM) selectively over normal cells. Synergizes with FDA-approved drugs such as doxycycline and nicolsamide as well as natural compounds such as berberine. Selectively inhibits the growth of Gram-positive over Gram-negative bacteria.

Application Procedures

First dissolved in DMSO up to 50 mg/ml, or Ethanol (25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Research use only.

Additional information

Datasheet:

TBI3781_Dodecyl-TPP

MSDS:

TBI3781_Dodecyl-TPP_MSDS_2024

Research use only.