CHS-828 (GMX-1778), NAMPT inhibitor (TBI1390)
$90.00 – $360.00
NAMPT inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1390-5MG | Yes | 5 MG | $90.00 | |||
TBI1390-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: N-[6-(4-chlorophenoxy)hexyl]-N’-cyano-N”-4-pyridinyl-guanidine
Alternate Names: GMX-1778
Molecular Formula: C19H22ClN5O
Formula Weight: 371.86
CAS Number: 200484-11-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO up to 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
NAMPT inhibitor
Functions
A potent and selective inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme in the biosynthesis of NAD, which may be used to deplete cells of NAD. Displays potent cytotoxic effects in tumor cells. Displays antitumor activity in vivo. Increases ROS levels in cancer cells but not in normal cells.
Application Procedures
First dissolved in DMSO up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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