CFM-4, CARP-1 mimetic (TBI1493)
$126.00 – $504.00
CARP-1 mimetic
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1493-5MG | Yes | 5 MG | $126.00 | |||
TBI1493-25MG | Yes | 25 MG | $504.00 |
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Description
Product Details
Formal Name: 1-[(2-Chlorophenyl)methyl]-5′-phenyl-spiro[3H-indole-3,2′(3’H)-[1,3,4]thiadiazol]-2(1H)-one
Molecular Formula: C22H16ClN3OS
Formula Weight: 405.90
CAS Number: 331458-02-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (greater than 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
CARP-1 mimetic
Functions
CARP-1 functional mimetic. Interferes with CARP-1 binding to APC-2 (IC50=10-15 μM). Enhances CARP-1 expression and induces G2/M cell cycle arrest. Induces apoptosis and suppresses growth of medulloblastoma cells and malignant pleural mesothelioma cells.
Application Procedures
First dissolved in DMSO (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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