Bafilomycin A1, Vacuolar H+ ATPase inhibitor (TBI2060)
$72.00 – $288.00
Vacuolar H+ ATPase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2060-100UG | Yes | 100 UG | $72.00 | |||
TBI2060-1MG | Yes | 1 MG | $288.00 |
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Description
Product Details
Formal Name: (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyl-oxacyclohexadeca-3,5,11,13-tetraen-2-one
Molecular Formula: C35H58O9
Formula Weight: 622.84
CAS Number: 88899-55-2
Purity: >98%
Formulation: Lyophilized
Solubility: Soluble in DMSO (up to 5 mg/ml, with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Vacuolar H+ ATPase inhibitor
Functions
Macrolide antibiotic derived from Streptomyces griseus that is a potent and selective inhibitor of vacuolar H+-ATPases (IC50 = 0.6 – 1.5 nM). Inhibits autophagy via disruption of fusion between autophagosomes and lysosomes.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml, with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 1 MG, 100 UG |
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