CD38 (Cyclase) Activity Assay Kit (Fluorometric) (TBS2100)
$490.00
SKU | Stock | SIZE (test) | Price | Quantity | ||
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TBS2100-100 | Yes | 100 Tests | $490.00 |
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Description
CD38, also known as ADP-ribosyl cyclase, is a multifunctional ectoenzyme expressed in many immune cells including CD4+, CD8+, B lymphocytes and natural killer cells. It functions in cell adhesion, signal transduction and calcium signaling. CD38 is involved in the metabolism of nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP). The results are the production of Ca2+-mobilizing compounds, such as cyclic ADP ribose (cADPR) and ADP ribose (ADPR). CD38 is used as a marker for poor prognosis in chronic lymphocytic leukemia and multiple myeloma and is an attractive cancer immunotherapy drug target.
Tribioscience’s CD38 Assay Kit is a simple and fast fluorometric assay that measures the cyclase activity of CD38 in biological samples. CD38 catalyzes the conversion of nicotinamide guanine dinucleotide (NGD+) to cyclic GDP-ribose (cGDPR) which can be measured by fluorometric method at Ex/Em=300 nm/410 nm.
Applications
- Measure CD38 Cyclase activity in a variety of samples.
Storage Conditions
Store the Reagent at -20°C, protect it from light. Shelf life: 12 months.
Standard Curve
Additional information
SIZE (test) | 100 Tests |
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Datasheet:
TBS2100 CD38 Cyclase activity Fluorometric_assay datasheet-V01-2024
MSDS:
TBS2100 CD38 Cyclase Activity Assay Kit (Fluorometric 100 Assays)_MSDS
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