InVivo Anti-Mouse VTCN1/B7-H4 Monoclonal Antibody (TBS10402)
$489.00 – $2,399.00
Target: V-set domain containing T-cell activation inhibitor 1, B7 homolog 4, B7-H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, Vtcn1, B7h4.
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBS10402-0.5MG | Yes | 0.5 MG | $489.00 | |||
| TBS10402-1MG | Yes | 1 MG | $719.00 | |||
| TBS10402-5MG | Yes | 5 MG | $2,399.00 |
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Description
Description
Tribio in vivo Anti-Mouse VTCN1/B7-H4 Monoclonal Antibody is a highly specific mouse monoclonal antibody targeting mouse VTCN1 (B7-H4). It specifically recognizes and can block the biological activity of B7-H4 by interfering with its inhibitory signaling on T cells, making it suitable for research applications such as ELISA, flow cytometry, and functional neutralization assays. B7-H4 is an immune checkpoint protein that negatively regulates T cell activation and proliferation, playing a key role in maintaining immune tolerance and modulating immune responses. It is overexpressed in various tumors, where it contributes to immune evasion, tumor progression, and poor prognosis. Therefore, this antibody is widely used in studies of tumor immunology, autoimmune diseases, and immune regulation, including research in ovarian, breast, renal, and lung cancers.
Product Details
| Applications: | ELISA, FCM, Neutralization |
| Species reactivity: | Mouse |
| Host: | Mouse |
| Isotype: | IgG2a, kappa |
| Target:
|
V-set domain containing T-cell activation inhibitor 1, B7 homolog 4, B7-H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, Vtcn1, B7h4. |
| Uniprot: | Q7TSP5 |
| Concentration: | 3 mg/ml |
| Purity: | >95% |
| Formulation: | Liquid |
| Storage buffer: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Clonality: | Monoclonal |
| Storage: | Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles. |
Data Image
Fig. 1. Flow-cytometry using anti-human VTCN1 antibody.
Un-transfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human VTCN1 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC and cells analyzed on a NovoCyte Flow Cytometer.
Research use only.
Additional information
| SIZE (mg) | 1 MG, 5 MG, 0.5 MG |
|---|
Datasheet:
TBS10402 InVivo Anti-Mouse VTCN1 Monoclonal Antibody_Datasheet
MSDS:
TBS10402 InVivo Anti-Mouse VTCN1 Monoclonal Antibody_MSDS
Research use only.
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