InVivo Anti-Human Claudin-3 (CLDN3) Monoclonal Antibody (TBS10380)

$489.00$2,399.00

Target: Claudin 3, Clostridium perfringens enterotoxin receptor 2, CPE-R 2, CPE-receptor 2, Rat ventral prostate.1 protein homolog, hRVP1, CLDN3, C7orf1, CPETR2.

SKU: TBS10380 Categories: ,
SKUStock SIZE (mg) PriceQuantity
TBS10380-0.5MG Yes 0.5 MG $489.00
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TBS10380-1MG Yes 1 MG $719.00
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TBS10380-5MG Yes 5 MG $2,399.00
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Description

Description

Tribioscience in vivo Anti‑Human CLDN3/Claudin‑3 Antibody (CDN04) is a mouse‑derived monoclonal antibody (IgG2a, κ) that specifically binds to the human tight‑junction protein Claudin‑3 (also known by aliases such as CPE‑R2, hRVP1, C7orf1, and the Clostridium perfringens enterotoxin receptor 2), a four‑transmembrane domain molecule critical for epithelial cell–cell adhesion and barrier function. This reagent is supplied for neutralization applications and is validated for reactivity with human Claudin‑3, making it suitable for functional studies aimed at blocking Claudin‑3 activity in vitro. Claudin‑3 is widely studied in epithelial biology and oncology, as its expression is frequently upregulated in a range of carcinomas including ovarian, breast, colorectal, pancreatic, prostate, and other epithelial cancers, and is explored as both a biomarker and therapeutic target due to its altered expression and accessibility during tumorigenesis.

Product Details

Applications: Neutralization
Species reactivity: Human
Host: Mouse
Isotype: IgG2a, kappa
Target: Claudin 3, Clostridium perfringens enterotoxin receptor 2, CPE-R 2, CPE-receptor 2, Rat ventral prostate.1 protein homolog, hRVP1, CLDN3, C7orf1, CPETR2.
Uniprot: O15551
Concentration: 3 mg/ml
Purity: >95%
Formulation: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Clonality: Monoclonal
Storage: Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles.

Data Image

 

Fig. 1. SDS-PAGE for InVivo Anti-Human CLDN3/Claudin-3 Antibody

MW: Molecular Weight (kDa) Marker.

R: Reducing conditions.

NR: Non-Reducing conditions.

Research use only.

Additional information

SIZE (mg)

1 MG, 5 MG, 0.5 MG

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