Anti-Mouse PD-1 Mouse Monoclonal Antibody (LALAPG) (TBS10218)

$246.00$4,301.00

Alternative names: programmed cell death protein 1; PD-1; PD1; CD279; cluster of differentiation 279

SKU: TBS10218 Category:
SKUStock SIZE (mg) PriceQuantity
TBS10218-0.5 Yes 0.5 MG $246.00
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TBS10218-1 Yes 1 MG $352.00
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TBS10218-5 Yes 5 MG $1,309.00
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TBS10218-25 Yes 25 MG $4,301.00
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Description

Description: Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor expressed on the surface of immune cells, including T cells, B cells, and myeloid cells. It plays a crucial role in immune regulation by delivering inhibitory signals upon interaction with its ligands, PD-L1 and PD-L2, to reduce T cell activity and maintain immune homeostasis. This antibody also contains a LALAPG mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors.

Applications:

  • in vivo blocking of PD-1/PD-L signaling

Molecular Weight: 150 kDa

Host: Mouse

Isotype: Mouse IgG2a Kappa

Mutations: L234A L235A P329G (LALAPG)

Concentration: 4 mg/ml

Purity: >95%

Formulation: PBS, pH 7.0, no stabilizers or preservatives.

Endotoxin: < 1EU/mg

Clonality: Monoclonal

Sterility: 0.2 µm filtered

Storage: Stable at 4°C for one month. Store at -20°C for long-term storage.

Research use only.

Additional information

SIZE (mg)

1 MG, 25 MG, 5 MG, 0.5 MG

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