In-vivo Anti-Human CD274/PD-L1/B7-H1 Monoclonal Antibody (TBS10389)
$489.00 – $2,399.00
Target: Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1, B7 homolog 1, B7-H1, CD274, CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1.
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBS10389-0.5MG | Yes | 0.5 MG | $489.00 | |||
| TBS10389-1MG | Yes | 1 MG | $719.00 | |||
| TBS10389-5MG | Yes | 5 MG | $2,399.00 |
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Description
Description
Tribioscience in vivo Anti-Human CD274/PD-L1/B7-H1 Monoclonal Antibody is a human IgG1, kappa monoclonal antibody specifically targeting PD-L1 (Programmed Cell Death 1 Ligand 1, CD274, B7-H1, PDCD1L1, PDL1, hPD-L1). PD-L1 is a membrane-associated immune checkpoint protein that plays a critical role in regulating T cell activity and tumor immune evasion. This antibody is particularly relevant for research in areas such as cancer immunotherapy, autoimmune diseases, and immune checkpoint modulation, where PD-L1 expression contributes to disease progression and therapeutic targeting.
Product Details
| Applications: | FuncS |
| Species reactivity: | Human |
| Host: | Mouse |
| Isotype: | IgG2a, kappa |
| Target:
|
Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, hPD-L1, B7 homolog 1, B7-H1, CD274, CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1. |
| Uniprot: | Q9NZQ7 |
| Concentration: | 3 mg/ml |
| Purity: | >95% |
| Formulation: | Liquid |
| Storage buffer: | 0.01M PBS, pH 7.4. |
| Purification: | Protein A/G purified from cell culture supernatant. |
| Clonality: | Monoclonal |
| Storage: | Store -20°C up to 12 months, and -80°C for long term. Avoid repeated freeze-thaw cycles. |
Data Image
Fig. 1. SDS-PAGE for InVivo Anti-Human/Mouse CD274/PD-L1/B7-H1 Antibody
MW: Molecular Weight (kDa) Marker.
R: Reducing conditions.
NR: Non-Reducing conditions.
Fig. 2. Flow-cytometry using anti-human CD274 antibody. Un-transfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD274 monoclonal antibody at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC and cells analyzed on a NovoCyte Flow Cytometer.
Fig. 3. Flow-cytometry using PE anti-human CD274 antibody.
MDA-MB-231 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD274 monoclonal antibody (Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Fig. 4. Flow-cytometry using APC anti-human CD274 antibody.
MDA-MB-231 cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD274 monoclonal antibody (Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Fig.5. Flow-cytometry using FITC anti-human CD274 antibody.
MDA-MB-231 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD274 monoclonal antibody (Catalog: HV974010, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
Research use only.
Additional information
| SIZE (mg) | 1 MG, 5 MG, 0.5 MG |
|---|
Datasheet:
TBS10389 InVivoMAb Anti-Human CD274 Antibody_Datasheet
MSDS:
TBS10389 InVivoMAb Anti-Human CD274 Antibody_MSDS
Research use only.
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