CRANAD-2 (TBS0016)
$32.00 – $1,180.00
Synonyms: Curcumin-derived near-infrared fluorescent probe, Aβ-targeting fluorescent probe
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBS0016-1 | Yes | 1 MG | $32.00 | |||
| TBS0016-10 | Yes | 10 MG | $149.00 | |||
| TBS0016-20 | Yes | 20 MG | $289.00 | |||
| TBS0016-100 | Yes | 100 MG | $1,180.00 |
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Description
Tribio CRANAD-2 is a curcumin-derived near-infrared fluorescent probe for the detection of amyloid-β (Aβ) deposits in vitro and in vivo. It exhibits high affinity for Aβ (Kd = 38 nM). Upon binding to Aβ aggregates, CRANAD-2 displays an approximately 70-fold increase in fluorescence intensity, a blue shift in emission from 805 nm to 715 nm, and a significant increase in quantum yield, making it a valuable probe for Aβ imaging in Alzheimer’s disease research.
PROPERTIES
| Formal Name: | (T-4)-[(1E,6E)-1,7-bis[4-(dimethylamino)phenyl]-1,6-heptadiene-3,5-dionato-kO3,kO5]difluoro-boron |
| CAS No.: | 1193447-34-5 |
| Molecular Formula: | C23H25BF2N2O2 |
| Formula Weight: | 410.3 |
| Purity: | ≥98% |
| Form: | A crystalline solid |
| λmax: | 595 nm |
| Storage: | Store at -20°C, Protected from light |
| Stability: | ≥ 4 years |
APPLICATION
- Detection of amyloid-β (Aβ) deposits in vitro and in vivo
- Near-infrared fluorescence imaging of Aβ plaques
- Alzheimer’s disease research
- Evaluation of Aβ-targeting therapeutics
- Molecular imaging of amyloid pathology
Research use only.
Additional information
| SIZE (mg) | 1 MG, 10 MG, 20 MG, 100 MG |
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