Lenvatinib, VEGFR kinase inhibitor (TBI3313)
$99.00 – $396.00
VEGFR kinase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI3313-5MG | Yes | 5 MG | $99.00 | |||
TBI3313-25MG | Yes | 25 MG | $396.00 |
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Description
Product Details
Formal Name: 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
Alternate Names: E7080
Molecular Formula: C21H19ClN4O4
Formula Weight: 426.85
CAS Number: 417716-92-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
VEGFR kinase inhibitor
Functions
A potent inhibitor of VEGFR2 and R3, IC50s=4.0 and 5.2 nM respectively. Also inhibits VEGFR1, FGFR1, PDGFR3b and Kit, IC50s=22, 46, 39 and 100 nM respectively. Suppresses lymph node and lung metastasis in human mammary breast tumor model. Suppresses tumor cell migration and invasion. Inhibits angiogenesis.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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