IWR-1 endo, Tankyrase inhibitor (TBI5081)
$90.00 – $360.00
Tankyrase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI5081-5MG | Yes | 5 MG | $90.00 | |||
TBI5081-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: 4-(1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl)-N-8-quinolinyl-benzamide
Molecular Formula: C25H19N3O2
Formula Weight: 409.40
CAS Number: 1127442-82-3
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 10 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Tankyrase inhibitor
Functions
A potent inhibitor of Wnt signaling (IC50=180 nM). Inhibits zebrafish tailfin regeneration (0.5 mM). Acts via inhibition of tankyrase and attenuates wnt/β-catenin signaling in cancer stem-like cells. Promotes self-renewal and maintains pluripotency of human embryonic stem cells. Promotes differentiation of pluripotent stem cells into cardiomyocytes.
Application Procedures
First dissolved in DMSO (up to at least 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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