A939572, SCD1 inhibitor (TBI4639)

Description

Product Details

Formal Name: 4-(2-Chlorophenoxy)-N-[3-(methylcarbamoyl)phenyl]piperidine-1-carboxamide

Molecular Formula: C₂₀H₂₂ClN₃O₃

Formula Weight: 387.86

CAS Number: 1032229-33-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

 

Applications

SCD1 inhibitor

 

Functions

Potent stearoyl-CoA desaturase 1 (SCD1) inhibitor (IC50s = mouse: <4 nM, human: 37 nM). Active in various cancer models alone and in combination with other chemotherapeutics. A939572 was able to selectively eliminate human pluripotent stem cells (hPSCs) in the presence of progenitor and differentiated cells.

 

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Additional information

SIZE (mg)	25 MG, 5 MG

Datasheet:

TBI4639_A939572

MSDS:

TBI4639_A939572_MSDS_2024