ABT-418 HCl, Nicotinic acetylcholine receptor agonist; Cognition enhancer (TBI1470)
$162.00 – $648.00
Nicotinic acetylcholine receptor agonist; Cognition enhancer
| SKU | Stock | SIZE (mg) | Price | Quantity | ||
|---|---|---|---|---|---|---|
| TBI1470-5MG | Yes | 5 MG | $162.00 | |||
| TBI1470-25MG | Yes | 25 MG | $648.00 |
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Description
Product Details
Formal Name: 3-Methyl-5-(1-methyl-2(S)-pyrrolidinyl)isoxazole hydrochloride
Molecular Formula: C9H14N2O HCl
Formula Weight: 202.68
CAS Number: 147388-83-8
Purity: >98%
Formulation: powder
Solubility: Soluble in Water (up to 15 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Nicotinic acetylcholine receptor agonist; Cognition enhancer
Functions
Agonist at neuronal nicotinic acetylcholine receptors displaying the highest potency at α4β2 and α2β2 subtypes (EC50= approximately 6 and 11 μM, respectively). Displays anxiolytic activity in a rat model and was 6-fold more potent than diazepam. Reduces distractibility in a primate model and may have relevance in attention deficit hyperactivity disorder. Improves cognition in Alzheimer’s disease patients.
Application Procedures
First dissolved in Water (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 3 months.
Additional information
| SIZE (mg) | 25 MG, 5 MG |
|---|
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