NSC-663284, Cdc25 Phosphatase inhibitor (TBI1352)
$162.00 – $630.00
Cdc25 Phosphatase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI1352-5MG | Yes | 5 MG | $162.00 | |||
TBI1352-25MG | Yes | 25 MG | $630.00 |
- Description
- Terms
- Additional information
- Documents
- Reviews (0)
Description
Product Details
Formal Name: 6-Chloro-7-[[2-(4-morpholinyl)ethyl]amino]-5,8-quinolinedione
Molecular Formula: C15H16ClN3O3
Formula Weight: 321.77
CAS Number: 383907-43-5
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 55 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Cdc25 Phosphatase inhibitor
Functions
Potent, selective and irreversible inhibitor of CDC25 phosphatases, Ki=29, 95 and 89 nM for human CDC25A, B2 and C respectively and >20- and >450-fold selective over VHR and PTP1B. Arrests cells at G1 and G2/M and inhibits cdk1 and 2 activation. Inhibits the growth of a variety of human tumor cell lines. Acts via irreversible oxidation of the catalytic cysteine of CDC25.
Application Procedures
First dissolved in DMSO (up to 15 mg/ml), or in Ethanol (up to 55 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
---|
Be the first to review “NSC-663284, Cdc25 Phosphatase inhibitor (TBI1352)”
You must be logged in to post a review.
Reviews
There are no reviews yet.