LH-846, Casein kinase 1d inhibitor (TBI1465)
$99.00 – $360.00
Casein kinase 1d inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1465-5MG | Yes | 5 MG | $99.00 | |||
TBI1465-25MG | Yes | 25 MG | $360.00 |
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Description
Product Details
Formal Name: N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneaceramide
Molecular Formula: C16H13ClN2OS
Formula Weight: 316.81
CAS Number: 639052-78-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml with warming).
Storage: RT
Stability: ≥ 1 year.
Applications
Casein kinase 1d inhibitor
Functions
Potent and selective inhibitor of casein kinase (CK) 1δ., IC50s=0.29, 1.3 and 2.5 μM for δ, ε and α isoforms respectively with no inhibition of CK2. Inhibits CK1δ-mediated phosphorylation and degradation of PER1 protein and lengthens circadian period in U2OS cells.
Application Procedures
First dissolved in DMSO (up to 20 mg/ml) or in Ethanol (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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