Etomoxir (+) Na, Carnitine palmitoyltransferase Inhibitor (TBI4731)
$126.00 – $486.00
Carnitine palmitoyltransferase Inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4731-5MG | Yes | 5 MG | $126.00 | |||
TBI4731-25MG | Yes | 25 MG | $486.00 |
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Description
Product Details
Formal Name: (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt
Molecular Formula: C15H18ClO4·Na
Formula Weight: 320.74
CAS Number: 828934-41-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 5 mg/ml with warming)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Carnitine palmitoyltransferase Inhibitor
Functions
Etomoxir (828934-41-4) is an irreversible inhibitor of mitochondrial carnitine palmitoyl transferase 1 (CPT1). It is widely used to study fatty acid oxidation. Etomoxir has been investigated as a therapeutic agent for heart disease, diabetes, and cancer. Use of etomoxir in concentrations greater than 5 µM induces acute production of ROS with associated evidence of severe oxidative stress in proliferating T cells indicating a loss of specificity for CTP1 at these concentrations. 200 µM etomoxir inhibited complex I of the electron transport chain.
Application Procedures
First dissolved in DMSO (up to 5 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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