Deferasirox, Iron Chelator (TBI4949)
$90.00 – $243.00
Iron Chelator
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4949-10MG | Yes | 10 MG | $90.00 | |||
TBI4949-25MG | Yes | 25 MG | $243.00 |
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Description
Product Details
Formal Name: 4-[3,5-bis(2-Hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid
Alternate Names: ICL670
Molecular Formula: C21H15N3O4
Formula Weight: 373.36
CAS Number: 201530-41-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
Iron Chelator
Functions
Clinically useful iron chelator used in long term care of ß-thalassemia and other heavily transfused hematological patients. It has been shown to potent inhibitor of JumonjiC Domain-Containing Histone Demethylases (IC50’s = KDM4A(JMJD2A) 4.76 µM, KDM5A(JARID1A) 5.00 µM, KDM6B(JMJD3) 3.95 µM). Deferasirox has also been investigated as a potential anticancer agent.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 10 MG, 25 MG |
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