WZB117, GLUT1 Inhibitor (TBI4581)
$63.00 – $225.00
GLUT1 Inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4581-5MG | Yes | 5 MG | $63.00 | |||
TBI4581-25MG | Yes | 25 MG | $225.00 |
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Description
Product Details
Formal Name: 3-Fluoro-1,2-phenylene bis(3-hydroxybenzoate)
Molecular Formula: C20H13FO6
Formula Weight: 368.31
CAS Number: 1223397-11-2
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (greater than 25 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
GLUT1 Inhibitor
Functions
WZB117 is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 µM. Daily intraperitoneal injection of WZB117 at 10mg/kg resulted in 70% reduction in tumor volume of human A549 lung cancer grafted on nude mice.
Application Procedures
First dissolved in DMSO (greater than 25 mg/ml) or in Ethanol (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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