Vildagliptin, DPP4 inhibitor (TBI2887)
$79.00 – $234.00
DPP4 inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI2887-10MG | Yes | 10 MG | $79.00 | |||
TBI2887-50MG | Yes | 50 MG | $234.00 |
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Description
Product Details
Formal Name: (S)-1-[N-(3-Hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile
Alternate Names: LAF237
Molecular Formula: C17H25N3O2
Formula Weight: 303.40
CAS Number: 274901-16-5
Purity: >98%
Formulation: Powder
Solubility: Soluble in DMSO (up to 45 mg/ml), in DMF (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml)
Storage: -20°C
Stability: ≥ 2 years.
Applications
DPP4 inhibitor
Functions
A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1). Delaying the degradation of GLP-1 extends the action of insulin and suppressing the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia). Clinically useful antidiabetic agent. Ameliorates cognitive deficits in streptozotocin-induced Alzheimers disease model. Displays protective effects on β-cells by inhibition of ER stress in a mouse model.
Application Procedures
First dissolved in DMSO (up to 45 mg/ml), in DMF (up to 20 mg/ml), or in Ethanol (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO, DMF or Ethanol may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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