VAS-2870, Nox inhibitor (TBI1073)
$99.00 – $351.00
Nox inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1073-5MG | Yes | 5 MG | $99.00 | |||
TBI1073-25MG | Yes | 25 MG | $351.00 |
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Description
Product Details
Formal Name: 3-Benyl-7-(2-benzoxazolyl)yhio-1,2,3-triazolo(4,5-d)pyrimidine
Molecular Formula: C18H12N6OS
Formula Weight: 360.40
CAS Number: 722456-31-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 10 mg/ml) or in DMF (up to 25 mg/ml).
Storage: RT
Stability: ≥ 2 years.
Applications
Nox inhibitor
Functions
NAD(P)H oxidase (Nox) inhibitor. Abolishes PDGF-mediated Nox activation and ROS production (100% at 10 μM). Inhibits PMA-induced oxidative burst in HL-60 cells (IC50=2 µM). Enhances TGF-ß-induced apoptosis in liver tumor cells.
Application Procedures
First dissolved in DMSO (up to 10 mg/ml) or in DMF (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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