Umifenovir, Antiviral agent (TBI4472)
$90.00 – $324.00
Antiviral agent
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4472-10MG | Yes | 10 MG | $90.00 | |||
TBI4472-50MG | Yes | 50 MG | $324.00 |
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Description
Product Details
Formal Name: 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid, ethyl ester, monohydrochloride
Alternate Names: Arbidol
Molecular Formula: C22H25BrN2O3S • HCl
Formula Weight: 513.90
CAS Number: 131707-23-8
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to at least 15 mg/ml) or in Ethanol (up to at least 10 mg/ml)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Antiviral agent
Functions
Umifenovir (131707-23-8) is a broad-spectrum antiviral medication. It has shown activity against influenza A,B,and C, respiratory syncytial, SARS-CoV, adeno, parainfluenza type 5, polio, rhino, coxsackie, hanta, chikungungya, hepatitis B and C viruses. It blocks hemagglutinin-mediated membrane fusion of influenza virus particles. Umifenovir has recently been shown to inhibit SARS-CoV2 infection by blocking virus entry as well as release from endolysosomes during intracellular trafficking. It has been suggested that Umifenovir may block trimerization of the spike glycoprotein, a key step in host cell adhesion.
Application Procedures
First dissolved in DMSO (up to at least 15 mg/ml) or in Ethanol (up to at least 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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