Spastazoline, Spastin inhibitor (TBI4240)
$198.00 – $711.00
Spastin inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI4240-5MG | Yes | 5 MG | $198.00 | |||
TBI4240-25MG | Yes | 25 MG | $711.00 |
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Description
Product Details
Formal Name: N-(5-tert-Butyl-1H-pyrazol-3-yl)-2-[(3R)-3-propan-2-ylpiperazin-1-yl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Molecular Formula: C20H30N8
Formula Weight: 382.52
CAS Number: 2351882-11-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Spastin inhibitor
Functions
Spastazoline in as ATP-competitive inhibitor (IC50 = 99 nM) of the microtubule-severing AAA protein spastin. It is selective against four related AAA proteins (XL-katarin, Hs-FIGL1, Mm-VCP, and Hs-PCH2). A new and interesting tool for the study of the assembly, disassembly, or maintenance of microtubule-based cellular structures.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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