Retinoic acid, Retinoid RAR agonist (TBI1138)
$54.00 – $108.00
Retinoid RAR agonist
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1138-50MG | Yes | 50 MG | $54.00 | |||
TBI1138-500MG | Yes | 500 MG | $108.00 |
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Description
Product Details
Formal Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Alternate Names: ATRA; Tretinoin
Molecular Formula: C20H28O2
Formula Weight: 300.44
CAS Number: 302-79-4
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 8 mg/ml) or in Ethanol (up to 15 mg/ml).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Retinoid RAR agonist
Functions
all−trans−Retinoic acid (ATRA; a metabolite of Vitamin A) is an endogenous ligand for the retinoic acid receptor (RAR). The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells. ATRA promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.
Application Procedures
First dissolved in DMSO (up to 8 mg/ml) or in Ethanol (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Additional information
SIZE (mg) | 500 MG, 50 MG |
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