Resiquimod (R848) (TBI2733)
$117.00 – $414.00
Toll-like receptor 7/8 agonist; Immunostimulant
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI2733-10MG | Yes | 10 MG | $117.00 | |||
TBI2733-50MG | Yes | 50 MG | $414.00 |
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Description
Product Details
Formal Name: 1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
Molecular Formula: C17H22N4O2
Formula Weight: 314-38
CAS Number: 144875-48-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml with warming)
Storage: -20°C
Stability: ≥ 1 year.
Applications
Toll-like receptor 7/8 agonist; Immunostimulant
Functions
A Toll-like receptor 7/8 agonist. May be used as an immune adjuvant in cancer vaccines. Resiquimod-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Topical treatment of wild-type mice induces systemic autoimmune disease which may be used as a model of systemic Lupus erythematosus. Effect on stem cells depends on cell type5,6.
Application Procedures
First dissolved in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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