PP2, Src family kinase inhibitor (TBI1407)
$108.00 – $297.00
Src family kinase inhibitor
SKU | Stock | SIZE (mg) | Price | Quantity | ||
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TBI1407-5MG | Yes | 5 MG | $108.00 | |||
TBI1407-25MG | Yes | 25 MG | $297.00 |
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Description
Product Details
Formal Name: 3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Molecular Formula: C15H16ClN5
Formula Weight: 301.78
CAS Number: 172889-27-9
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml with warming).
Storage: -20°C
Stability: ≥ 2 years.
Applications
Src family kinase inhibitor
Functions
Potent and selective Src family kinase inhibitor. Inhibits Lck(IC50=4 nM); Fyn (IC50=5 nM); Hck (IC50=5 nM). It displays weak inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50> 100 μM) and JAK2 (IC50> 50 μM). It is a useful probe for exploring the involvement of Src family kinases in signal transduction pathways.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 3 mg/ml with warming), then diluted to aqueous buffer. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Additional information
SIZE (mg) | 25 MG, 5 MG |
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