PNU-282987, Nicotinic acetylcholine receptor agonist; cognition enhancer (TBI4496)
$72.00 – $270.00
Nicotinic acetylcholine receptor agonist; cognition enhancer
SKU | Stock | SIZE (mg) | Price | Quantity | ||
---|---|---|---|---|---|---|
TBI4496-10MG | Yes | 10 MG | $72.00 | |||
TBI4496-50MG | Yes | 50 MG | $270.00 |
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Description
Product Details
Formal Name: N-(3R)-1-Azabicyclo[2.2.2}oct-3-yl-4-chlorobenzamide
Molecular Formula: C14H17ClN2O
Formula Weight: 264.75
CAS Number: 123464-89-1
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Nicotinic acetylcholine receptor agonist; cognition enhancer
Functions
PNU 282987 is a selective α7 nicotinic acetylcholine receptor (nAChR) agonist (Ki = 26 nM). The α7 nAChR is a potential therapeutic target of cognitive deficits in diseases such as Alzheimers, Parkinsons, schizophrenia, and attention deficit disorders – agonism of this receptor with PNU 282987 has shown potential to ameliorate these deficits.
Application Procedures
First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.
Additional information
SIZE (mg) | 10 MG, 50 MG |
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